MBMB 451b
Lecture #3
You can click on the link to listen to a RealAudio file of
the day's lecture. The following description contains the material
discussed and the source of the overheads used during the presentation.
- Code:
- ECN = Created by me
- PDF = pdf file
- S = Segel (Enzyme Kinetics)
- VV = Voet & Voet (Biochemistry)
Lecture 3 (1/25/00) 73
minutes
- Announcements
- Remember to check the web site for
RealAudio lectures and other materials
- Practice the problems at the end of
each chapter
- Lecture #2 review
- Rates of enzymatic reactions, chemical
kinetics, enzyme kinetics, inhibition
- Bonus problem
for bonus credit due in class on 8 February 2000
- Rates of enzymatic reactions (PDF
file for this topic)
- Inhibition, mixed inhibition (VV
Fig 13-13, S Figs III-16, III-17, III-18, III-13, VV Table 13-2)
- Effects of pH, ionization constants
(Figs 13-14, 13-15)
- Bisubstrate reactions, terminology,
rate equations, diffferentiating bisubstrate mechanisms, isotope
exchange (PDF pp 6, 7, VV Figs 13-18, 13-17, Table 13-3,
S Table IX-6, PDF pp. 8, 9)
- Enzymatic catalysis (PDF
file for this topic)
- Catalytic mechanisms, acid-base catalysis,
covalent catalysis, metal ion catalysis (PDF pp. 1, 2,
VV p. 372, ECN, VV Figs
14-1, p. 374, 14-2, 14-3, PDF p. 3, VV Figs 14-4, 14-5, PDF p.
4, VV pp. 376-377)
- Preview of lecture #4
- Enzymatic catalysis, lysozyme, serine
proteases, glutathione reductase
Remember to look over the Study Guides and textbook sections
for additional illustrations that may assist in your understanding
of the presented material.
MBMB451b
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