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Eric C. Niederhoffer, Ph.D. Associate Professor of Biochemistry and Molecular Biology Southern Illinois University School of Medicine 600 Agriculture Drive, Carbondale, IL 62901-6503 Rm 112 Lindegren, 618-453-6467 eniederhoffer@siumed.edu Copyright 2000- , E.C. Niederhoffer. All Rights Reserved. All trademarks and copyrights are the property of their respective owners.

Manganese-containing arginase (1rla) from Rattus norvegicus (rat) and the nickel-containing urease (1fwj) from Klebsiella aerogenes

• What structural elements are present?
• What is the subunit composition of the proteins?
• What are the major features of the active sites?

Kanyo, Z. F., L. R. Scolnick, D. E. Ash, and D. W. Christianson. 1996. Structure of a unique binuclear manganese cluster in arginase. Nature 383:554557.

Pearson, M. A., L. O. Michel, R. P. Hausinger, and P. A. Karplus. 1997. Structures of Cys319 variants and acetohydroxamate-inhibited Klebsiella aerogenes urease. Biochemistry 36:8164-8172.

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