Cytochrome c oxidase (2occ) oxidized

Cytochrome c oxidase (1ocr) reduced

• Push the button  to observe subunit I along with the possible channels:

H⁺ pumping channel 1 (red)

H⁺ pumping channel 2 (green)

H⁺ pumping channel 3 (orange)

H⁺ channel for water release (yellow)

Water channel (blue)

• Push the button  to observe H⁺ pumping channel 1:

Arg38, Asn451, Asp51, Ser441, Ser454, Ser461, Thr424, Tyr54, Tyr371, Tyr440

• Push the button  to observe H⁺ pumping channel 2:

Asn11, Asn98, Asp91, His12, His503, Ser101, Ser108, Ser115, Ser142, Ser149, Ser156, Ser157, Thr146, Tyr19

• Push the button  to observe H⁺ pumping channel 3:

Arg38, Asn451, Asp407, Gln428, His413, Ser382, Ser454, Ser461, Thr424, Tyr443

• Push the button  to observe H⁺ channel for water release:

Asn491, His240, His256, His291, His368, Lys265, Lys319, Ser255, Thr316, Thr489, Thr490, Tyr244

• Push the button  to observe the water channel:

Arg178, Arg438, Asn180, Asp173, Asp227, Asp364, Asp369, Gln232, Glu198, His233, His368, Thr294, Tyr129

• Push the button  to observe subunit I along with the possible channels:

H⁺ pumping channel 1 (red)

H⁺ pumping channel 2 (green)

H⁺ pumping channel 3 (orange)

H⁺ channel for water release (yellow)

Water channel (blue)

• Push the button  to observe H⁺ pumping channel 1:

Arg38, Asn451, Asp51, Ser441, Ser454, Ser461, Thr424, Tyr54, Tyr371, Tyr440

• Push the button  to observe H⁺ pumping channel 2:

Asn11, Asn98, Asp91, His12, His503, Ser101, Ser108, Ser115, Ser142, Ser149, Ser156, Ser157, Thr146, Tyr19

• Push the button  to observe H⁺ pumping channel 3:

Arg38, Asn451, Asp407, Gln428, His413, Ser382, Ser454, Ser461, Thr424, Tyr443

• Push the button  to observe H⁺ channel for water release:

Asn491, His240, His256, His291, His368, Lys265, Lys319, Ser255, Thr316, Thr489, Thr490, Tyr244

• Push the button  to observe the water channel:

Arg178, Arg438, Asn180, Asp173, Asp227, Asp364, Asp369, Gln232, Glu198, His233, His368, Thr294, Tyr129