"Chime Square" Animations Molecular Graphics Resource

Eric C. Niederhoffer, Ph.D. Associate Professor of Biochemistry and Molecular Biology Southern Illinois University School of Medicine 600 Agriculture Drive, Carbondale, IL 62901-6503 Rm 112 Lindegren, 618-453-6467 eniederhoffer@siumed.edu Copyright 2000- , E.C. Niederhoffer. All Rights Reserved. All trademarks and copyrights are the property of their respective owners.

Three forms of deoxyribonucleic acids, A-DNA (David Marcey, CLU), B-DNA (1bna), and Z-DNA (2zna)

• Where are the major and minor grooves?
• How are the base pairs oriented?
• What are the dimensions of each helix?

Drew, H. R., R. M. Wing, T. Takano, C. Broka, S. Tanaka, K. Itakura, and R. E. Dickerson. 1981. Structure of a B-DNA dodecamer: conformation and dynamics. Proc. Natl. Acad. Sci. U.S.A. 78:2179-2183.

Wang, A. J., G. J. Quigley, F. J. Kolpak, G. van der Marel, J. H. van Boom, and A. Rich. 1981. Left-handed double helical DNA: variations in the backbone conformation. Science 211:171-176.

Chime Square

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eniederhoffer@siumed.edu