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Eric C. Niederhoffer, Ph.D. Associate Professor of Biochemistry and Molecular Biology Southern Illinois University School of Medicine 600 Agriculture Drive, Carbondale, IL 62901-6503 Rm 112 Lindegren, 618-453-6467 eniederhoffer@siumed.edu Copyright 2000- , E.C. Niederhoffer. All Rights Reserved. All trademarks and copyrights are the property of their respective owners.

Triosephosphate isomerase (6tim) from Trypanosoma brucei brucei

• What structural elements are present in each molecule?
• What is the subunit composition?
• Which residues are likely to act as general acid and base catalysts?

Noble, M. E., R. K. Wierenga, A. M. Lambeir, F. R. Opperdoes, A. M. Thunnissen, K. H. Kalk, H. Groendijk, and W. G. Hol. 1991. The adaptability of the active site of trypanosomal triosephosphate isomerase as observed in the crystal structures of three different complexes. Proteins 10:50-69.

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