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Eric C. Niederhoffer, Ph.D.

Associate Professor of Biochemistry and Molecular Biology

Southern Illinois University School of Medicine
600 Agriculture Drive, Carbondale, IL 62901-6503
Rm 112 Lindegren, 618-453-6467
eniederhoffer@siumed.edu
Copyright 2000- , E.C. Niederhoffer.
All Rights Reserved. All trademarks and copyrights are the property of their respective owners.
Cobalamin-containing methylmalonyl-coenzyme A mutase (1req) from Propionibacterium freudenreichii shermanii

Mancia, F., N. H. Keep, A. Nakagawa, P. F. Leadlay, S. McSweeney, B. Rasmussen, P. Bosecke, O. Diat, and P. R. Evans. 1996. How coenzyme B12 radicals are generated: the crystal structure of methylmalonyl-coenzyme A mutase at 2 Å resolution. Structure 4:339-350.

Methylmalonyl-coenzyme A mutase (1req)

Active Site View

  • Push the button  to observe the following residues within 3.0 Å of the cobalamin:
Ala139, Ala373, Arg207, Glu370, Gly609, His610, Leu657, Ser655, Thr709, Tyr89, Val206, and nine water molecules

Push button  for Original View

 

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eniederhoffer@siumed.edu