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Eric C. Niederhoffer, Ph.D.
Associate Professor of Biochemistry
and Molecular Biology
- Southern Illinois University School
of Medicine
- 600 Agriculture Drive, Carbondale,
IL 62901-6503
Rm 112 Lindegren, 618-453-6467
- eniederhoffer@siumed.edu
- Copyright 2000-
,
E.C. Niederhoffer.
- All Rights Reserved.
All trademarks and copyrights are the property of their respective
owners.
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Catabolite gene activator protein
in the absence (1g6n) and presence of DNA (1ber)
from Escherichia coli
- What structural elements are present
in the protein?
- What is the subunit composition?
- What is the distance between protein
and DNA?
- What characteristics can be discovered
regarding the structure of DNA in the complex?
- Can you locate the coactivator?
Passner, J. M., S. C. Schultz,
and T. A. Steitz. 2000.
Modeling the cAMP induced allosteric transition using the crystal
structure of CAP-cAMP at 2.1 Å resolution. J. Mol. Biol.
304:847-859.
Parkinson, G., C. Wilson,
A. Gunasekera, Y. W. Ebright, R. E. Ebright, and H. M. Berman. 1996. Structure of the CAP-DNA complex
at 2.5 Å resolution: a complete picture of the protein-DNA
interface. J. Mol. Biol. 260:395-408.
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