MBMB 451b

Carbohydrate Metabolism Quiz

 

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  1. The synthesis and degradation of glycogen in muscle is not a futile (ATP-hydrolyzing) cycle because:

    glycogen synthase and phosphorylase are simultaneously activated.

    when glycogen synthase is inactivated, phosphorylase is simultaneously activated.

    glycogen binds Mg2+, thereby lowering the concentration of MgATP2-.

    cyclic AMP activates adenylate kinase.

    of the Pasteur effect.


  2. Which one of the following is the most correct?

    NAD is used in glycolysis and in the pentose phosphate shunt.

    NAD is used in glycolysis, but not in the pentose phosphate shunt.

    NADP is used in glycolysis and in the pentose phosphate shunt.

    NADP is used in glycolysis, but not in the pentose phosphate shunt.

    NAD and NADP are both used in oxidative phosphorylation.


  3. The hexose monophosphate shunt pathway is utilized for all of the following EXCEPT which one?

    formation of ATP

    generation of NADPH

    ribose-5-phosphate synthesis

    ribose-5-phosphate degradation

    synthesis of pentoses


  4. Which of the following is a tricarboxylic acid?

    oxaloacetic acid

    succinic acid

    a-ketoglutaric acid

    citric acid

    acetic acid


  5. Which one of the following substances can be formed directly by a carbon dioxide fixation reaction?

    glucose

    glutamine

    lactic acid

    pyruvic acid

    oxaloacetic acid


  6. The reduced coenzyme of glycerol phosphate dehydrogenase, located in the mitochondrial membrane, is oxidized by:

    NADH dehydrogenase.

    coenzyme Q (ubiquinone).

    cytochrome c.

    cytochrome oxidase.

    cytochrome a.


  7. The glycerol phosphate shuttle functions in:

    anaerobic glycolysis for regeneration of NAD.

    lipid catabolism.

    aerobic glycolysis to transport NADH equivalents resulting from glycolysis into mitochondria.

    triglyceride synthesis.


  8. Which of the following are functions of the TCA cycle?
    1. The generation of NADH and reduced flavins.
    2. The formation of a-ketoglutarate.
    3. The oxidation of acetyl-CoA produced from glycolysis and fatty acid oxidation.
    4. The utilization of excess ATP generated by glycolysis.

    1, 2, and 3 are correct.

    1 and 3 are correct.

    2 and 4 are correct.

    only 4 is correct.

    all four are correct.


  9. Which of the following metabolic processes in the cell proceed by different pathways in the forward and reverse directions, under physiological conditions?
    1. Glucose ´ glucose 6-phosphate.
    2. Fructose 6-phosphate ´ fructose 1,6-bisphosphate.
    3. Phosphoenolpyruvate ´ pyruvate.
    4. 1,3-Bisphosphoglycerate ´ 3-phosphoglycerate.

    1, 2, and 3 are correct.

    1 and 3 are correct.

    2 and 4 are correct.

    only 4 is correct.

    All four are correct.


  10. The hexose monophosphate shunt:
    1. can convert glucose to carbon dioxide in the absence of oxygen.
    2. can provide five carbon sugars when the cell's needs for nucleotides is high.
    3. would have a diminished role in the metabolism of glucose in individuals with glucose 6-phosphate dehydrogenase deficiency.
    4. can provide the cell with NADH needed in the synthesis of fatty acids.

    1, 2, and 3 are correct.

    1 and 3 are correct.

    2 and 4 are correct.

    only 4 is correct.

    all four are correct.


 

 

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