MBMB 451b
Lecture #11
You can click on the link to listen to a RealAudio file of
the day's lecture. The following description contains the material
discussed and the source of the overheads used during the presentation.
- Code:
- ECN = Created by me
- PDF = pdf file
- VV = Voet & Voet (Biochemistry)
Lecture 11 (2/22/00) 75
minutes
- Announcements
- Check MBMB451b web site for RealAudio
lectures, additional course materials, and sample problems
- Bonus problem
for bonus credit due in class on 29 February 2000
- Lecture #10 review
- Glycogen metabolism, control of glycogen
metabolism, glycogen storage diseases
- Citric acid cycle, cycle overview,
metabolic sources of acetyl-coenzyme A
- Citric acid cycle (PDF
file for this topic)
- Metabolic sources of acetyl-coenzyme
A, control of pyruvate dehydrogenase (PDF p. 6, VV Fig
19-10)
- Enzymes of the citric acid cycle, citrate
synthase, aconitase, NAD+-dependent isocitrate dehydrogenase,
a-ketoglutarate
dehydrogenase, succinyl-CoA synthetase, succinate dehydrogenase,
fumarase, malate dehydrogenase, integration of the citric acid
cycle (PDF p. 7, VV Fig 19-12, PDF p. 8, VV Fig 19-13,
PDF p. 9, VV Fig 19-14, PDF pp. 10, 11, VV Fig 19-15, PDF p.
12, VV p. 553, Fig 19-16, PDF p. 13, VV Fig 19-17, PDF p. 14,
VV p. 556, PDF p. 15)
- Regulation of the citric acid cycle
(VV Table 19-2, PDF pp. 16, 17, VV Fig 19-8)
- The amphibolic nature of the citric
acid cycle (PDF pp. 18, 19, VV Fig 19-19)
- Electron transport and oxidative
phosphorylation (PDF file for this topic)
- The mitochondrion, mitochondrial anatomy,
mitochondrial transport systems (PDF p. 1, VV Fig 20-1,
PDF p. 2, VV Figs 20-2, 20-3, PDF p. 3, VV Figs 20-4, 20-5, 20-6,
20-7)
- Electron transport, thermodynamics
of electron transport, the sequence of electron transport (PDF
p. 4, 5)
- Note correction to Electron transport
and oxidative phosphorylation PDF p. 4, DG = -nFDeo'
- Preview of lecture #12
- Electron transport and oxidative phosphorylation
- Other pathways of carbohydrate metabolism
Remember to look over the Study Guides and textbook sections
for additional illustrations that may assist in your understanding
of the presented material.
MBMB451b
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