MBMB 451b
Lecture #7
You can click on the link to listen to a RealAudio file of
the day's lecture. The following description contains the material
discussed and the source of the overheads used during the presentation.
- Code:
- ECN = Created by me
- PDF = pdf file
- VV = Voet & Voet (Biochemistry)
Lecture 7 (2/8/00) 74
minutes
- Announcements
- MBMB451b web site has all RealAudio
lectures to date and additional course materials
- New sample problems have been posted
on the home page and individual lecture pages
- Bonus problem for credit due by the
end of class today
- Lecture #6 review
- Sugars and polysaccharides, glycoproteins
- Introduction to metabolism, metabolic
pathways, organic reaction mechanisms
- Introduction to metabolism (PDF
file for this topic)
- Experimental approaches to the study
of metabolism, metabolic inhibitors, growth studies, and biochemical
genetics, isotopes in biochemistry, isolated organs, cells, and
subcellular organelles (PDF pp. 11, 12, VV Table 15-1,
Fig 15-17, PDF p. 13)
- Thermodynamics of phosphate compounds,
phosphoryl-transfer reactions, rationalizing the "energy"
in "high-energy" compounds, the role of ATP (PDF
pp. 14, 15, VV Fig 15-21, PDF p. 16, VV Table 15-3, Figs 15-22,
15-23, 15-24, PDF p. 17, VV Figs 15-25, 15-26, 15-27)
- Oxidation-reduction reactions, the
Nerst equation, measurement of redox potentials, concentration
cells (PDF pp. 18, 19, VV Table 15-4)
- Thermodynamics of life, living systems
cannot be at equilibrium, nonequilibrium thermodynamics and the
steady state, thermodynamics of metabolic control (PDF
p. 20, VV Fig 15-30)
- Glycolysis
(PDF file for this
topic)
- The glycolytic pathway, historical
perspective, pathway overview (PDF p. 1, VV Fig 16-1,
PDF p. 2, VV Fig 16-3)
- Preview of lecture #8
- Glycolysis, the reactions of glycolysis,
fermentation: the anaerobic fate of pyruvate, control of metabolic
flux, metabolism of hexoses other than glucose
- Glycogen metabolism
Remember to look over the Study Guides and textbook sections
for additional illustrations that may assist in your understanding
of the presented material.
MBMB451b
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