MBMB 451b

Copyright 2000, E.C. Niederhoffer

Lecture #1

You can click on the link to listen to a RealAudio file of the day's lecture. The following description contains the material discussed and the source of the overheads used during the presentation.

Code:

ECN = Created by me

PDF = pdf file

VV = Voet & Voet (Biochemistry)

Lecture 1 (1/18/99) 73 minutes

Announcements

• Welcome from ECN and PH, syllabus, website, resources, grading policy, teleconference, RealAudio lectures
• Springfield students - There will be no teleconference of the lecture on 2/17/00

Introduction to enzymes

• Historical perspective (ECN)
• Substrate specificity, stereospecificity, geometric specificity (VV Figs 12-1, 12-3, ECN)
• Coenzymes, cofactors, prosthetic groups, vitamins (ECN)
• Regulation of enzymatic activity, availability, activity, ATCase (ECN, VV Figs 12-5, 12-9)
• Enzyme nomenclature, classification system (ECN)

Rates of enzymatic reactions

• Chemical kinetics, elementary reactions, rates of reactions, transition state theory (VV Figs 13-1, 13-2, 13-5)

Remember to look over the Study Guides and textbook sections for additional illustrations that may assist in your understanding of the presented material.

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